I Took Melatonin Every Day for 3 Months and Here’s What Happened

@adriansrfr says:

If you take a negligible quantity of anything, then I’d expect negligible results too

@BillyRubinIII says:

RAY PEAT: “Okay, you mentioned the hormones estrogen and how it relates to melatonin. With increasing age, people have made a big thing of the fact that melatonin, which peaks about 3AM in everyone, that this peak is a little bit smaller in old age. But it happens that…with aging, as the thyroid decreases, the melatonin decreases, because when thyroid is active, your melatonin comes up as an antioxidant defence against that the high metabolic rate that thyroid can stimulate. So when your thyroid is low, the melatonin is low, when your thyroid is high, the melatonin is high, in a logical adaptation — because it is an antioxidant.

But the function of melatonin all by itself, when it isn’t surrounded by the appropriate other conditions, melatonin, in studies done in pig tissue, by a man named (Sirotkin?), pigs are relatively close to humans in having daytime habits, night time sleep and so on, which is very important for melatonin because it’s a night time dominant hormone — in pigs, he found that melatonin suppresses progesterone and raises estrogen, and this happens to be the same thing that low thyroid does.

So if the melatonin rises in proportion to your thyroid, it doesn’t matter that it is having these pro-estrogen, anti-progesterone effects, because the thyroid is doing exactly the opposite to those hormones and is taking care of the situation, because thyroid gets rid of the excess estrogen while…being totally responsible for producing progesterone. But if you take melatonin out of context, as he did in the pig study, you’re going to get an exactly anti-thyroid effect, deranging those hormones in the direction of stress and aging.

Some of the current publicity that is used to promote the fact that melatonin is used to make you go to sleep, it happens to be also a thing that goes up during hibernation, and its function is to lower the body temperature, and remember the hospitalized patients — the ones who had the lowest temperatures were the least likely to survive, because as the thyroid goes down and your body temperature falls, you lose a lot of your immune functions and tissue repair capacity. So lowering your body temperature does make you hibernate and it does make you sleep, but you don’t want to use something out of context to force that.

The studies that have been used to advocate melatonin’s possibly anti-aging effect were done on mice and rats, and it turns out that they are very opposite to human beings and pigs, because they work at night in general and sleep in the daytime, and so melatonin for them has exactly the opposite meaning that it does for people and pigs. And for example, in humans and rats, melatonin raises prolactin, but in humans, prolactin knocks out progesterone production and causes infertility and stress and osteoporosis for example.

But in rats, it happens, and mice, it happens…prolactin raises their progesterone, and progesterone has the pro-life, anti-aging effect. So melatonin has been confused by a lot of this rodent based research which is opposite in many ways to what it does in people and pigs.” Gary Null interview 1996

@Andrew-0815 says:

I have been taking 1 mg melatonin for a few weeks now and have been sleeping perfectly ever since. I’m in my 40s.

@MrKrueger88 says:

I’ve been taking 100mg daily … And sleeping better than ever . New studies show it’s very beneficial in many ways .