Leading Longevity Scientist Predicts Dramatic Life Extension by 2035 – Aubrey de Grey

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Timestamps:
00:00 Introduction
00:37 Twenty since Aubrey coined the Longevity Escape Velocity
11:13 When will we reach Longevity Escape Velocity
16:45 Slowing down aging vs regeneration
19:44 What breakthroughs we need for longevity escape velocity
24:00 Seven types of aging damage that needs to be repaired
24:37 Loss of cells and stem cells
33:57 Regenerating limbs and organs
36:10 Mitochondrial free radical theory of aging
41:15 Intracellular and Extracellular waste products
47:15 How far is gene therapy now?
49:15 Death resistant cells
53:52 Do you need long telomeres
57:15 Extracellular matrix stiffening and glycation
01:00:48 Biggest breakthroughs in the next 5 years
01:04:30 What to do to live until the longevity escape velocity

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  • @SiimLand says:

    Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
    Timestamps:
    00:00 Introduction
    00:37 Twenty since Aubrey coined the Longevity Escape Velocity
    11:13 When will we reach Longevity Escape Velocity
    16:45 Slowing down aging vs regeneration
    19:44 What breakthroughs we need for longevity escape velocity
    24:00 Seven types of aging damage that needs to be repaired
    24:37 Loss of cells and stem cells
    33:57 Regenerating limbs and organs
    36:10 Mitochondrial free radical theory of aging
    41:15 Intracellular and Extracellular waste products
    47:15 How far is gene therapy now?
    49:15 Death resistant cells
    53:52 Do you need long telomeres
    57:15 Extracellular matrix stiffening and glycation
    01:00:48 Biggest breakthroughs in the next 5 years
    01:04:30 What to do to live until the longevity escape velocity

  • @AceKinG2024 says:

    I yet to hear from this guys a single practical advice on how to reverse aging. None. He always come up with nonsense terms

  • @AceKinG2024 says:

    Caloric restriction is not fasting. And fasting mimicking supplements and diets is not fasting. Nothing can mimick fasting. You need to target lots of pathways at once

    • @phyju says:

      BUT they are money making things to keep business going. Imagine if the whole western world realised they could be so more healthy by not eating. And when you do eat you eat only fresh produce… They will never let that happen with there drugged up food that has withdrawl symptoms.

    • @StraitjacketFitness says:

      “Need”.

  • @dinomiles7999 says:

    Peptides❤ ! Don’t die ❤Decentralization ❤

  • @aakuster says:

    Transhumanist nonsense, this channel has officially Jumped the Shark.

    • @snusnu39 says:

      This channel has always been about longevity.

    • @serioserkanalname499 says:

      Not wanting to rot away and die in pain due to the grinding wheel of time is about as transhumanist as not wanting to die of sepsis because you cut your toe on a random rock in the forest.

  • @phyju says:

    I posted a reply yet YouTube took it down. You can’t bag big business using food with withdrawal symptoms to keep you not willing to fast… Maybe using different words with the same meaning works?

    • @StraitjacketFitness says:

      The decision not to fast rests with the individual. The food industry is not responsible for an individual’s and irresponsibility and weakness.
      I intentionally subject myself to ranges of moderate to severe caffeine withdrawal accompanied by 16-24 hour fasts 2 to 3 times a week.
      Having to go through withdrawal is not an excuse for being a 🐱.

  • @Biohacker24 says:

    Stoked for this episode 🙌🏽

  • @jheichelbech says:

    Aubrey’s take on methylene blue?

  • @NikolaFoster-jo6ys says:

    While a lot of this is speculation, I’m not sure many people appreciate how likely a lot of this is to become a reality. It’s just a question of time and money. If all of the West were to devote its efforts and resources to this end, LEV would pretty much become a certainty in the next decade or so. That’s why, speculation though it may be, it’s incredibly important to make more people aware of this research and secure more funding.

  • @Hail2MasterChief says:

    Awesome. Thanks Siim!

  • @johnmausteller says:

    Sounds good to me

  • @nocternbemsi5619 says:

    I like you Siim but Aubrey is a fraud

  • @serioserkanalname499 says:

    “Right to try” should be introduced everywhere in the world.
    Because mice trials just dont cut it.
    On the other hand, I’m pretty sure solving brain-computer interfaces and immune-rejection will probably be a lot easier than solving all the problems the body accumulates with age and I dont see the problem with replacing an organ with a machine to live longer… except the brain of course.

  • @ilyab.5127 says:

    My secret to longevity is “not to die every single day!”

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