Podcast: Supplements for Preventing Alzheimer’s

@lukeweaver9287 says:

Subtract caffeine, and you’ll save $$ on most of those supplements

@in2caffeine says:

@lukeweaver9287  caffeine’s potential neuroprotective effects:

1. Adenosine receptor blockade – reduces excitotoxicity and oxidative stress

2. Antioxidant properties – helps reduce oxidative stress

3. Reduction of inflammation – lowers brain inflammation

4. Enhanced autophagy – promotes cellular cleanup of damaged components

5. Improved mitochondrial function – supports energy production in neurons

@in2caffeine says:

best to get an ATN blood test, then intervene if you are concerned with cognitive decline. hsCRP to a lesser indicator biomarker. start with low dose lithium for several months. rapamycin can be a second addition. However, that latter is not a suppliment. repa and metformin to hit the metabolic pathway, lithium is orthogonal to metabolism. so hit it from both directions.