Topical Retinoids to Reverse Skin Aging
Tretinoin, also known as all-trans retinoic acid (sold under a variety of brands including Retin-A), can reverse the signs of aging skin, but at what cost?
What Is the Most Important Anti-Aging Cream Ingredient? ( ). That was the question posed and answered in my previous video. In the next two videos, I look at the benefits of topical niacinamide ( ) and topical vitamin C ( ).
For more on how to live your longest, healthiest life, preorder my new book How Not to Age ( ). (As always, all proceeds I receive from all of my books ( ) are donated to charity.)
New subscribers to our e-newsletter always receive a free gift. Get yours here: .
Have a question about this video? Leave it in the comment section at and someone on the NutritionFacts.org team will try to answer it.
UPDATE: We are currently testing the removal of the comment section across all video pages on the NutritionFacts.org website until October, and it will either be reinstated thereafter or removed permanently based on the results. Please feel free to continue your discussions by commenting on our YouTube channel and social media accounts, where we will have Health Support volunteers available to address questions.
Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at . You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics.
Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM
Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources:
• Subscribe:
• Donate:
• Podcast :
• Books:
• Shop:
• Facebook:
• Twitter:
• Instagram:
Now thats a game changer 👏🏼
Mary Kay makes a very effective retinol cream combined with a calming lotion. No scripts needed.
God, this is confusing! Retinal, retinal, retinadehyde, retinyl palmitate, tretinoin… and have seen ads for granactive retinoids.
Main takeaway seems to be that prevention is best (use sunscreen, or protect yourself from the sun using other methods). The pictures he showed of wrinkle reduction didn’t seem that convincing to me, even if they’re statistically significant.
@@pdblouin not mutually exclusive – I use both! But the sunscreen won’t reverse damage only protect against new damage. The retinol products I’ve used have def made a difference. I think the benefits are v well proven now. It’s just a minefield picking my way through v similar sounding ingredients! 🙂
@@pdblouin
I generally agree with you but many have sworn (vs placebo group) that their wrinkles have diminished with tretinoin/retinol.
Trentinoin made me feel so anxious, I had to stop it!!! Crazy!!
That wasn’t the tretinoin, it was your anxiety.
@@davin8r is it not possible that Trentinoin can make anxiety worse?
@@davin8r the implication was that the anxiety returned to previous level when they stopped use. And the video acknowledged that it can be absorbed systemically, meaning that it doesn’t just stay on the skin. So it’s entirely possible that it could have any number of effects. If other users experienced similar symptoms it would be worthwhile to investigate, since so many people have interest in using these products.
That’s Placebo
Scientists can’t figure out which of the retinblah tretinbleh compounds help because they themselves got all confused with the names.
No they didn’t get confused. They have a separate name for each version. It’s just confusing to people who don’t study this topic closely enough to understand the differences. And the information presented here is what some of the results are, of studies that have done so far. As usual, there is no “magic bullet”. Some of them help, some help more than others, some have more side effects than others. If you want to mock the science, then maybe you should become a scientist and do a better study.
I’m tired of seeing people who barely know the first thing about science, dumping on science like they know better.
And don’t get me started on all the science deniers that use smartphones and don’t see the irony.
@@aaronsuever4362 Evidently you are not able to determine if a statement is humorous sarcasm.
Just stop using those creams and use lemon juice on a cotton swap and rub it on your face . Cucumber and watermelon to moisturize there.
I expect any expert talking about reversing skin aging to show their face and be a picture of healthy glowing timeless skin themselves.
Ouch!
Then you clearly don’t know much about how and why scientific research studies are done.
You confuse human scientists with perfect omnipotent robogods
@@mediokritet Greger is not a scientist. That’s laughable.
I put kale juice on my face.
Kale is king
You are what you eat! Including your skin!!!
It’s pronounced “tret-in-O-in”, doc.😉
I thought so to, but google puts the emphasis on the ti
I’m Indian, I use Tretinoin 0.01% gel every night, then slug.
Use sunscreen everyday!
Wear UV 400 glasses.
Most people think I’m in my 20s, meanwhile I’m approaching 35😂
CeraVe has a great easy non irritating retinol…. By the way I bought Treninoin gel in Greece recently ,Corfu exactly at the pharmacy .. So becoming less available but still there … Also Thailand has it ..
The Ordinary’s retinol 1% is great!
So what’s the final answer here? None of them?
I’m wondering the same. Takeaway, please…🙏